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Adherence to Antiretroviral Therapy and Cd4 T-Cell Count Responses Among HIV-Infected Injection Drug Users.
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OBJECTIVE: To evaluate the time to CD4 cell count response (> or = 50 cells/mm3) among patients initiating highly active antiretroviral therapy (HAART) with and without a history of injection drug use, and to examine the potential role of non-adherence to HAART on differential CD4 responses. METHODS: Population-based analysis of treatment-naive patients initiating HAART during the period 1 August 1996 to 31 July 2000 and who were followed until 31 March 2002. Patients were stratified based on 95% adherence and history of injection drug use, and Kaplan-Meier methods and Cox regression were used to evaluate CD4 response rates and factors associated with CD4 responses. (Journal Abstract: Antiviral Therapy 9: 229-235)
Journal
2004
Antiviral Therapy
9
2
229235-35
London
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A Canadian Homelessness Research Network (CHRN) initiative. The CHRN has received financial support from the Government of Canada’s Homelessness Partnering Strategy and the Social Science and Humanities Research Council of Canada