This report summarizes findings from a study conducted from 2013-16 of expanding Housing First (HF) in six Canadian communities: Fraser Valley, BC, Saskatoon, SK, Winnipeg, MB, Waterloo and York Regions, ON, and Halifax, NS. This research project, “Transforming Housing and Treatment Services for Chronically Homeless Persons with Mental Illness in Canada: A Systems Approach to Integrated Knowledge Translation,” was funded through the Canadian Institutes of Health Research’s (CIHR) Partnerships for Health Systems Improvement (PHSI) program. The aim of this PHSI project was to examine the implementation of HF in the six communities, through training and technical assistance (TTA) and networking, supported by the Mental Health Commission of Canada (MHCC). Following the success of MHCC’s At Home / Chez Soi research demonstration project, MHCC strived to expand the HF approach to new Canadian communities, as well as sustaining and enhancing existing HF programs.