Canada’s first national poverty reduction strategy, “Opportunity for All” is a welcomed move forward for those working to eliminate poverty in Canada. The Tamarack Institute’s Vibrant Communities is dedicated to supporting cities in getting the most out of the strategy to support their work in reducing poverty in their community. As part of The Tamarack Institute’s partnership agreement with the Employment and Social Development Canada, we have committed to supporting cities to be part of implementing the national strategy. One way that Vibrant Communities will be supporting cities is through the development of a TEN Guide for Cities Implementing the Federal Strategy. To start the conversation for the TEN Guide, this article provides an introduction to the national strategy, background into why cities are crucial in poverty reduction, examples of work already being done by cities and some initial thoughts on how community-based organization can get the most out of the national strategy.